Does myelin decrease with age

The more myelin and myelination an.The unique metabolic demands of producing and maintaining their vast myelin sheaths and synthesizing the brain's cholesterol supply make oligodendrocytes especially susceptible to a variety of insults.The integrity of the myelin sheath decreases with age, and so does the amount of myelin in the brain.Myelin acts like the protective and.Degeneration of myelin itself does not seem to result in microglial cells undertaking phagocytosis.

For people with ms, the attacks are directed at the central nervous system (cns) — specifically at myelin, a substance that coats the nerves.Once you are in your late 50's, your oligodendrocytes will slow down their production of myelin.Studies have shown us that as we age, myelin breakdown and repair is continually occurring over the brain's entire 'neural network.For comparative purposes, we evaluated ultrastructural alternations and changes in.In autoimmune diseases, the immune system attacks the body's own tissues.